Biodegradable/disintegrable nanohybrids for photothermal theranostics

Nanohybrids using biocompatible and biodegradable materials are explored for their photothermal mediated theranostic applications. These hybrids so chosen that they biodegradable. Gold-based different nanosystems have NIR absorption which is highly favored PTT, but limited by toxicity, stability, clearance. To overcome these challenges, we demonstrated thermosensitive liposome-gold hybrid nanosystem therapy its clearance in vivo the first time. We also possibility of same as drug (curcumin) carrier triggered delivery were successful curcumin an adjuvant to PTT. Thermoresponsive polymers coated with gold X-ray imaging deep seated tumors has been evaluated. Fluorescent Poly (ethylene glycol) encapsulated metal nanoparticles synthesized application cancer theranostics explored. Biodegradable polymer (PLGA) liposomes loaded anticancer plant fraction a dye showed synergistic photo-chemo against in-vitro & in-vivo. The intracellular changes PTT mechanistic action anti-cancer agent detail.